The journal publishes research on blood pressure regulation, hypertension mechanisms, cardiovascular outcomes, and treatment strategies.

Article types include original research, clinical trials, systematic reviews, meta analyses, cohort studies, qualitative research, brief reports, and case series.

• Original research with full methods and outcome reporting
• Systematic reviews with protocol and search strategy
• Short reports with focused findings and limitations
• Case series with clear clinical learning points

Confirm that the manuscript fits journal scope and that all authors agree on the submission and authorship order.

• Verify the article type and reporting guideline
• Check ethics approvals, consent statements, and registrations
• Prepare data availability and funding statements
• Review reference accuracy and include DOIs when available

Authors may send a brief presubmission inquiry to confirm scope fit before full submission.

Include a working title, structured abstract, study design, and a short statement of clinical relevance for blood pressure care.

• Describe study design and primary outcomes
• Include target population and setting
• Note trial registration or protocol identifiers
• State data availability and ethical approvals

A concise cover letter helps editors understand clinical relevance and blood pressure impact.

• Summarize the main contribution and clinical relevance
• Explain why the work fits hypertension priorities
• Disclose prior dissemination or preprints
• Identify any special considerations for reviewers

• Title page with author details and affiliations
• Structured abstract with objectives, methods, results, and conclusion
• Keywords aligned with hypertension outcomes
• Main text with Introduction, Methods, Results, and Discussion
• Funding, conflict of interest, and author contributions
• References with complete citation details and DOI when available

Use consistent terminology for blood pressure measurement, treatment protocols, and outcome definitions.

Use clear headings, consistent numbering, and readable formatting that supports reviewer feedback.

• Use a standard, readable font and consistent spacing
• Define abbreviations at first use
• Keep tables and figures close to their first citation
• Ensure captions are complete and understandable

Use consistent units for blood pressure and cardiovascular measures, and define abbreviations on first use.

• Provide units for all measurements and laboratory values
• Use standard hypertension terminology throughout
• Avoid unexplained abbreviations in tables and figures
• Keep acronyms consistent between abstract and main text

The title page should include full author names, affiliations, and corresponding author contact details.

Abstracts should report key numerical findings, effect sizes when available, and conclusions tied to the data.

Provide ORCID identifiers when available to support accurate attribution and indexing.

All studies involving human participants require ethics approval and informed consent. Report trial registration details for interventional studies.

• Ethics approval identifiers and oversight body
• Informed consent statements and privacy protections
• Clinical trial registration before enrollment
• Conflict of interest and funding disclosures

Research involving vulnerable populations should include additional protections and justification for inclusion.

Interventional studies should be registered prior to enrollment. Provide registry identifiers and describe protocol changes.

Describe treatment protocols clearly, including dosage, timing, and monitoring methods.

Include a data availability statement describing where data can be accessed or why access is restricted.

• Public repositories such as Zenodo, Figshare, Dryad, or OSF
• Institutional repositories with persistent identifiers
• Controlled access repositories for sensitive clinical data

If code or analytical scripts were used, provide repository links and version details.

When data cannot be shared, explain the restriction clearly and provide a process for qualified access when feasible.

Cite datasets and software in the reference list with persistent identifiers to support reuse and attribution.

Describe quality control procedures, data cleaning steps, and validation checks.

Transparent workflows strengthen confidence in hypertension outcomes and reduce review delays.

• CONSORT for randomized trials
• PRISMA for systematic reviews and meta analyses
• STROBE for observational studies
• CARE for case reports

Provide a clear statistical methods section and report key assumptions.

Describe study setting, recruitment, inclusion and exclusion criteria, and sample size rationale.

Define primary and secondary outcomes before analysis and report protocol deviations with their impact on interpretation.

• Describe blinding and randomization procedures where applicable
• Report missing data handling and sensitivity analyses
• State software versions and statistical packages
• Justify subgroup analyses and multiple comparison adjustments

Describe measurement devices, cuff sizing, calibration procedures, and measurement timing.

Report whether readings were office, home, or ambulatory and specify averaging protocols.

Provide complete details for pharmacologic interventions, including dosing, titration, and monitoring schedules.

For device based or digital interventions, describe device models, validation status, and calibration checks.

Specify validated instruments, scoring approaches, and clinically meaningful thresholds.

Report baseline values and change scores with confidence intervals when possible.

Describe imaging protocols, assay methods, and quality controls. Provide details on biomarker validation and clinical relevance.

Report adverse events and safety monitoring procedures, including severity grading and management steps.

Safety reporting is essential for pharmacologic and lifestyle interventions.

Submit figures in high resolution formats such as TIFF, JPEG, or PNG. Provide descriptive captions and reference every figure in the text.

Tables should be self explanatory with clear units and statistical reporting. Supplementary files can include extended methods or monitoring protocols.

Supplementary files can include care pathway diagrams, monitoring protocols, or patient education materials.

Provide clear file names and describe each item in the manuscript text.

Images should accurately reflect the original data. Any adjustments must be applied uniformly and described in the methods.

For clinical images, obtain consent for publication and remove identifying features unless explicit consent is documented.

Authors must obtain permission for any third party figures, tables, or instruments. Provide documentation with the submission.

Authorship should reflect substantial contributions to conception, design, data acquisition, analysis, or interpretation.

Provide a clear contributions statement for transparency and confirm that all authors approve the final manuscript.

State all funding sources, grant numbers, and sponsor roles. Disclose financial or non financial relationships that could influence interpretation.

If a sponsor had a role in study design or analysis, describe the role clearly.

If the manuscript has appeared as a preprint or conference abstract, disclose this in the cover letter and cite the source.

Manuscripts receive editorial screening followed by peer review. Provide a point by point response to reviewer comments.

Include a marked version showing changes when possible. Clear responses accelerate decisions and improve quality.

Accepted manuscripts move through copyediting, proof review, and production. Authors should verify accuracy of data, figures, and author details.

Prompt proof review accelerates publication timelines and supports accurate indexing.

• Missing ethics approval details
• Inconsistent outcome definitions or measurement periods
• Insufficient detail for replication
• Figures without clear captions or unit definitions
• Incomplete funding or conflict disclosures

Before submission, verify that all files are complete, consistent, and aligned with journal scope.

• Cover letter summarizing contribution and clinical relevance
• All figures and tables cited in the text
• Supplementary files labeled and referenced
• Data availability and ethics statements included

Clear writing and consistent reporting reduce review delays and improve clinical interpretation.

Ensure terminology for measurements, outcomes, and follow up intervals is consistent throughout the manuscript.

If language polishing is needed, consider optional editing before submission to improve clarity for reviewers.

Language editing is separate from peer review and does not influence editorial decisions.

The editorial office can clarify scope fit, reporting guidelines, and data availability expectations before submission.