Submit Your Pathophysiology Research to JSN
Join leading researchers advancing our understanding of disease mechanisms, molecular pathways, and pathogenesis
Two Convenient Submission Methods
Choose the submission pathway that best fits your workflow. Both methods provide secure, efficient manuscript handling with full tracking capabilities.
ManuscriptZone Portal
Our comprehensive submission platform designed for complete manuscript management from submission through publication.
- Real-time submission status tracking
- Auto-save functionality prevents data loss
- Direct access to reviewer comments
- Guided workflow with validation checks
- Revision management tools
- Communication hub with editorial team
Best for: Authors seeking full visibility and control throughout the publication process, especially for complex manuscripts with multiple revisions.
Submit via ManuscriptZoneQuick Submission Form
Streamlined submission process for straightforward manuscripts requiring minimal back-and-forth communication.
- No account registration required
- Single-page submission form
- Fast upload process
- Immediate confirmation email
- Simplified workflow
- Perfect for time-sensitive submissions
Best for: Authors with complete, submission-ready manuscripts who prefer a simplified, no-frills submission experience.
Use Quick Submission FormPathophysiology Research We Publish
The Journal of Spine and Neuroscience welcomes rigorous investigations into disease mechanisms, molecular pathways, and pathogenesis across neurological and spinal disorders. We prioritize mechanistic insights that advance our understanding of disease biology.
Original Research Articles
Novel investigations into disease mechanisms, molecular pathways, cellular dysfunction, and pathogenesis of neurological and spinal disorders.
Biomarker Discovery Studies
Identification and validation of molecular biomarkers for disease diagnosis, prognosis, or mechanistic understanding of pathological processes.
Disease Model Development
Novel in vitro, in vivo, or computational models that recapitulate disease pathophysiology and enable mechanistic investigation.
Molecular Pathway Analysis
Comprehensive investigations of signaling cascades, gene regulatory networks, and molecular mechanisms underlying disease progression.
Systematic Reviews & Meta-Analyses
Comprehensive synthesis of mechanistic evidence, pathway analyses, or biomarker studies with quantitative integration where appropriate.
Methods & Protocols
Novel experimental techniques, assay development, or methodological innovations for investigating disease mechanisms and molecular pathways.
Short Communications
Preliminary findings, novel observations, or rapid reports of significant mechanistic discoveries requiring timely dissemination.
Review Articles
Comprehensive, critical analyses of current understanding in specific areas of pathophysiology, highlighting knowledge gaps and future directions.
Our Focus: We prioritize mechanistic investigations that advance understanding of disease biology. Submissions should emphasize molecular mechanisms, cellular pathways, pathogenesis, and disease models rather than clinical diagnosis, treatment protocols, or patient management.
Pre-Submission Checklist
Ensure your manuscript is complete and properly formatted before submission. This checklist helps prevent delays and accelerates the review process.
Reporting Guidelines: We encourage adherence to discipline-specific reporting standards such as ARRIVE (animal research), CONSORT (clinical trials), STROBE (observational studies), and PRISMA (systematic reviews) to ensure methodological transparency and reproducibility.
Peer Review Timeline
We are committed to transparent, efficient peer review. Our expert reviewers in pathophysiology, neuroscience, and spinal research provide constructive feedback to strengthen your manuscript.
Submission & Initial Screening
Your manuscript undergoes administrative checks for completeness and adherence to submission guidelines. Plagiarism screening via iThenticate ensures originality.
1-3 daysEditor Assignment
An editor with expertise in your specific area of pathophysiology is assigned to handle your manuscript and oversee the peer review process.
2-4 daysPeer Review
Expert reviewers with specialized knowledge in disease mechanisms, molecular pathways, or relevant methodologies evaluate your manuscript for scientific rigor, novelty, and significance.
14-21 daysEditorial Decision
The editor synthesizes reviewer feedback and makes a decision: accept, minor revisions, major revisions, or reject. You receive detailed reviewer comments and editorial guidance.
21-28 days totalRevision & Re-review
If revisions are requested, you submit your revised manuscript with a detailed response to reviewers. The editor or reviewers assess whether concerns have been adequately addressed.
14 days re-reviewAcceptance & Production
Upon acceptance, your manuscript enters production for copyediting, typesetting, and final formatting. You review proofs before publication.
10 days to publicationAverage Timeline: From submission to publication, most manuscripts complete the process in approximately 60 days. Fast-track options are available for time-sensitive research with significant clinical or mechanistic implications.
Why Pathophysiology Researchers Choose JSN
Indexed Globally
Google Scholar ensures your research reaches the global pathophysiology community
Expert Reviewers
Specialists in disease mechanisms, molecular pathways, and pathogenesis provide rigorous, constructive peer review
Fast Decisions
Average 21 days to first decision with transparent communication throughout the review process
Open Access
Immediate, unrestricted access maximizes visibility and impact of your mechanistic discoveries
Ethical Standards
Committed to COPE publication ethics, research integrity, and transparent peer review practices
APC Waivers
Financial support available for researchers from low-income countries and unfunded studies
Submission Requirements
Manuscript Structure
Organize your manuscript with clear sections that facilitate peer review and reader comprehension:
- Title Page: Informative title, all author names and affiliations, corresponding author contact information
- Abstract: Structured abstract (Background, Methods, Results, Conclusions) not exceeding 300 words
- Keywords: 4-6 keywords reflecting main topics and methodologies
- Introduction: Clear statement of research question, rationale, and objectives within pathophysiology context
- Methods: Detailed description enabling reproducibility, including disease models, molecular techniques, and statistical analyses
- Results: Logical presentation of findings with appropriate figures and tables
- Discussion: Interpretation of results, mechanistic implications, limitations, and future directions
- Conclusions: Concise summary of key findings and their significance to understanding disease mechanisms
- References: Comprehensive citation of relevant literature in pathophysiology and related fields
Figures and Tables
High-quality visual presentation of data strengthens your manuscript:
- Submit figures as separate files in TIFF, EPS, or high-resolution JPEG format
- Minimum resolution: 300 DPI for photographs, 600 DPI for line art
- Include descriptive figure legends that enable standalone interpretation
- Tables should be editable (Word or Excel format) with clear column headers
- Number figures and tables consecutively in order of appearance
- Ensure all visual elements are referenced in the main text
Supplementary Materials
Additional data, extended methods, or supplementary figures can be included to support your main findings without cluttering the primary manuscript. Supplementary materials undergo peer review and are published online alongside your article.
Research Ethics & Integrity
The Journal of Spine and Neuroscience adheres to the highest standards of research ethics and publication integrity. All submissions must comply with the following requirements:
Human Subjects Research
- IRB/Ethics committee approval required for all studies involving human participants or human-derived materials
- Informed consent must be obtained and documented
- Patient privacy and confidentiality must be protected
- Include ethics approval number and institution name in Methods section
Animal Research
- IACUC or equivalent committee approval required for all animal studies
- Adherence to ARRIVE guidelines for reporting animal research
- Justification of animal model selection and sample size calculations
- Description of measures taken to minimize animal suffering
Data Integrity
- Original data must be available for verification if requested
- Image manipulation must not obscure, eliminate, or misrepresent information
- Statistical methods must be appropriate and clearly described
- Data sharing encouraged through public repositories where applicable
Authorship & Conflicts of Interest
- All authors must meet ICMJE authorship criteria
- Declare all financial and non-financial competing interests
- Acknowledge funding sources and sponsor roles
- Disclose any prior publication or presentation of the work
After Submission: What to Expect
Immediate Confirmation
Upon successful submission, you will receive an automated confirmation email with your manuscript tracking number. This number allows you to monitor your submission status through the ManuscriptZone portal.
Editorial Assessment
The editorial team conducts an initial assessment to ensure your manuscript aligns with the journal's scope in pathophysiology research. Manuscripts outside our focus area or lacking sufficient scientific rigor may be declined without external peer review to expedite the process for authors.
Peer Review Process
Manuscripts passing editorial screening are sent to expert reviewers with specialized knowledge in your research area. We employ single-blind peer review to ensure objective evaluation. Reviewers assess:
- Scientific rigor and methodological soundness
- Novelty and significance of mechanistic insights
- Clarity of presentation and logical flow
- Appropriateness of conclusions based on data
- Relevance to pathophysiology research community
Editorial Decision
Based on reviewer recommendations, the editor makes one of the following decisions:
- Accept: Manuscript accepted with minor editorial changes only
- Minor Revisions: Small changes required, typically re-reviewed by editor only
- Major Revisions: Substantial changes needed, manuscript returns to reviewers
- Reject: Manuscript does not meet publication standards or journal scope
Revision Submission
If revisions are requested, you will receive detailed feedback from reviewers and the editor. Submit your revised manuscript with:
- Point-by-point response to all reviewer comments
- Revised manuscript with changes highlighted
- Clean version of revised manuscript
- Any additional data or analyses requested by reviewers
Revised manuscripts should be submitted within 60 days to maintain priority in the review queue.
Ready to Submit Your Research?
Join the community of pathophysiology researchers advancing our understanding of disease mechanisms and molecular pathways.
Begin Your SubmissionNeed assistance with the submission process? Our editorial team is here to help: [email protected]