Overview
The Pancreas is a glandular organ in the upper abdomen, located near the duodenum, stomach, and bile duct, that performs both digestive (exocrine) and hormonal (endocrine) functions. Its exocrine tissue secretes enzymes that break down fats, proteins, and carbohydrates, while its endocrine islets produce hormones such as insulin and glucagon that regulate blood sugar. Because of these dual roles, pancreatic health is essential to digestion and metabolic balance. The Pancreas is subject to a range of disorders, including acute and chronic pancreatitis, cysts, autoimmune conditions, and tumors. Chronic pancreatitis can take distinct anatomical forms; for instance, groove pancreatitis is a rare segmental type that affects the "groove" region between the pancreatic head, the duodenum, and the common bile duct, often presenting with abdominal pain, weight loss, and vomiting and posing diagnostic challenges. Evaluation of pancreatic disease typically combines clinical assessment with imaging and, when needed, histology. Open-access research provides peer-reviewed studies and case reports on pancreatic anatomy, pancreatitis, and related diagnostic and management challenges.
Research published in this journal
1 peer-reviewed article, ranked by relevance. Each links to its DOI.