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Sep 2026
Massreshaw Assnakew AbebeCorresponding author
Gene therapy is a cancer treatment that is superior to chemotherapy, radiotherapy, and other less selective and specifically harmful forms of treatment. It entails the aberrant replacement, alteration, and deletion of a gene within a normal or healthy copy of a gene. Recent trials have made signific…
Sep 2019 DOI 10.14302/issn.2574-450X.jom-19-3001
Sikandar Hayat KhanCorresponding author
Gene therapy has entered a new era with the dawn of CRISPR/Cas9 technology which though were always available in nature but rediscovered to tame into a real-tlife genome editing tool. With the modernization upsurge and changes in ways the “homo sapiens” survived on this planet from hunger to current…
Apr 2018
Dongye LiCorresponding author
Heart failure(HF) is a disease with high morbility and mortality. The benefits of current pharmacological and device therapy for survival outcomes of patients with HF are limited. Gene therapy represents a novel promising strategy in treating HF, as it can theoretically normalize the aberrantly expr…
Mar 2021 DOI 10.14302/issn.2329-9487.jhc-21-3742
Tesfaye SisayCorresponding author
Cardiovascular disease is actually a major cause of mortality, illness and hospitalization worldwide. Several risk factors have been identified that are strongly associated with the development of cardiovascular disease. Public prevention strategies have relied predominately on managing environmenta…
Sep 2019 DOI 10.14302/issn.2572-5424.jgm-19-3024
Sikandar Hayat KhanCorresponding author
Background The objective of this review is to unify the various genetic defects along with elaborating metabolic pathways in Familial Combined Hyperlipidemia(FCHL) and also to differentiate the phenotype of FCHL from metabolic syndrome. Methods PubMed and Cochrane’s library was searched for keyword…
Aug 2017 DOI 10.14302/issn.2997-2086.jfs-17-1663
Michelle KnezevichCorresponding author
Fetal surgery is the newest surgical specialty with a compelling history. The development of fetal surgery began in primates and lambs and, in its most basic form, was first performed in humans in 1965. Since its introduction, the field has expanded and changed dramatically. Several of these changes…
Jan 2014 DOI 10.14302/issn.2328-0182.japst-12-183
Supriya D. MahajanCorresponding author
Gold nanorods (GNRs) are plasmonic nanostructures by virtue of their size-dependent optical properties, offer a bionanotechnology platform in areas of bioimaging, drug delivery etc for disease diagnosis, prognosis, and therapy. GNRs are more sensitive to changes in local environments, and offer stro…