Zaichick Vladimir, Zaichick Sofia, Age-Dependence of Some Trace Element Concentrations and their Ratios in Human Prostatic Fluid, Journal of Aging Research And Healthcare, Volume 2, Issue 4, 2019, Pages 11-20, ISSN 2474-7785, https://doi.org/10.14302/issn.2474-7785.jarh-19-2910. (https://oapgroup.org/jarh/article/1134) Abstract: The effect of age on Br, Fe, Rb, Sr, and Zn concentrations as well as on Zn/Br, Zn/Fe, Zn/Rb, and Zn/Sr content ratios in human prostatic fluid was investigated by 109Cd radionuclide-induced energy dispersive X-ray fluorescent microanalysis. Specimens of expressed prostatic fluid were obtained from 51 men (mean age 51 years, range 18-82 years) with apparently normal prostates using standard rectal massage procedure. Mean values (M ± SΕΜ) for concentration of trace elements (mg·L-1) in human prostate fluid were: Br 3.62±0.58, Fe 9.04±1.21, Rb 1.10±0.08, Sr 1.19±0.14, and Zn 573±28. Mean values for ratios of trace elements in human prostate fluid were: Zn/Br 523±103, Zn/Fe 105±16, Zn/Rb 661±63, and Zn/Sr 719±95. An age-related increase in Zn content and decrease in Br and Fe concentration was found. Moreover, the strongly pronounced increase in Zn/Br and Zn/Fe ratios was also observed. Keywords: variations with age in composition of human prostatic fluid; trace element concentration; trace element concentration ratios; energy dispersive X-ray fluorescent analysis